After selecting a potential new therapy for development, Hopen Therapeutics teams
up with leading researchers, research institutions, biotech firms, and pharmaceutical
companies. This collaborative approach gives us access to hundreds of experts who can
join us as needed – on short- or long-term assignments – as we develop products within
our invested companies.
Our collaboration strategy has a number of benefits:
- It gives us access to a rich pool of talent with a broad industry perspective.
- It keeps Hopen Therapeutics lean, efficient, and flexible, allowing us to expand
and shrink the size of a team as needed, depending on the task at hand.
- It encourages the experts on our teams to stay active in other projects within their
field. The knowledge, experiences, and relationships they gain through these related efforts
come back to benefit our business efforts.
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Hopen’s resource network offers a full range of scientific capabilities, allowing us
to build the best team for each selected opportunity. In drug development, for example,
these capabilities include:
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Target and Biomarker Discovery
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High throughput screening
Bio-informatics
Cheminformatics
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Analytical processing
In-vitro modeling
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Development: Lead Optimization, PK/PD, Pre-Clinical
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Lead chemistry
Medicinal chemistry
Structure activity
Compound synthesis
GLP development
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Mechanism of action
Optimization chemistry
Toxicology
Animal efficacy
Dosage optimization
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Clinical: Proof of Principle, Phases I-III
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Scale up
API production
cGMP clinical studies
Study design
Statistical powering
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Regulatory
Clinic access
Outpatient access
Clinician interface
Documentation
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Hopen Therapeutics, LLC has developed relationships with a variety of regional and national
institutions, and uses their resources to support idea development. Institutions include:
- Core Technology Alliance Corporation (CTA Corp.) Ann Arbor, Michigan
- Grand Valley State University Grand Rapids, Michigan
- Michigan State University East Lansing, Michigan
- University of California, San Diego - School of Medicine San Diego, California
- University of Michigan Ann Arbor, Michigan
- Van Andel Institute Grand Rapids, Michigan
- Western Michigan University Kalamazoo, Michigan
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